MSFT vs TMO Stock Comparison: Price, Growth & Valuation (2026)

Use MEXC Stock Compare for a detailed MSFT vs TMO analysis. Compare MSFT and TMO across price performance, growth, valuation, profitability and risk, based on market data and the latest reported financials.

MSFT vs TMO Stock Comparison Summary

MSFT reported year-over-year revenue growth of 17.8%, compared with 7.2% for TMO. Their P/E ratios are 28.7x and 35.8x, dividend yields are 0.69% and 0.27%, and 30-day volatility levels are 22.8% and 24.3%, respectively. These metrics highlight key differences in growth, valuation, dividend income and market risk. Overall MSFT leads across more of the selected comparison metrics.

Risk Disclaimer: MEXC Stock Compare provides information and comparisons on actual U.S.-listed stocks for reference only. Data may be delayed or inaccurate, does not constitute investment advice, and past performance does not guarantee future results.

MSFT vs TMO Stock Return Comparison (1W)

MSFTTMO

Compare the cumulative total returns of Microsoft Corp. (MSFT) and Thermo Fisher Scientific, Inc. (TMO) over the selected 1W period. Data as of 2026-09-28 12:00:00.

MSFT vs TMO Key Equity Metrics Comparison Summary

Microsoft Corp. (MSFT) has a market capitalization of $3.82T and operates in the Information Technology sector, with its main business classified under Systems Software. Its latest quarterly revenue changed +17.8% year over year.

Thermo Fisher Scientific, Inc. (TMO) has a market capitalization of $249.95B and operates in the Health Care sector, with its main business classified under Life Sciences Tools & Services. Its latest quarterly revenue changed +7.2% year over year.

MSFT vs TMO Key Stock Indicators

Comparison MetricMicrosoft Corp.
MSFT
Thermo Fisher Scientific, Inc.
TMO
Comparison results

Stock Price & Returns

Latest delayed stock price with 1-day, 1-month and year-to-date returns.

$514.751D: -1.3%1M: +0.4%1Y: +0.0%$676.001D: -0.7%1M: +8.6%1Y: +46.3%TMOWin

Market Capitalization

Total market value of the company's outstanding shares.

$3.82T$249.95BMSFTWin

Sector & Industry

The company's market sector and primary industry classification.

Information Technology / Systems SoftwareHealth Care / Life Sciences Tools & Services--
Based on delayed market data, MSFT is trading at $514.75, compared with $676.00 for TMO. Their market capitalizations are $3.82T and $249.95B, respectively. MSFT operates in the Information Technology sector, while TMO belongs to Health Care.
MSFT vs TMO Growth & Profitability

Revenue Growth (YoY)

Year-over-year change in revenue.

+17.8%+7.2%MSFTWin

EPS Growth (YoY)

Year-over-year change in earnings per share.

+31.7%+7.4%MSFTWin

ROIC

Return generated from invested capital.

26.6%7.8%MSFTWin

Gross Margin / Operating Margin

Profitability before and after operating expenses.

67.9% / 46.8%40.8% / 17.6%MSFTWin
On growth, MSFT posted revenue growth of +17.8% and TTM EPS growth of +31.7%. TMO, by comparison, posted revenue growth of +7.2% and TTM EPS growth of +7.4%.On profitability, MSFT recorded a gross margin of 67.9%, an operating margin of 46.8%, and ROIC of 26.6%. For TMO, the corresponding figures were 40.8%, 17.6%, and 7.8%.Overall, MSFT shows stronger overall growth and profitability.
MSFT vs TMO Valuation & Balance Sheet

Free Cash Flow Yield

Free cash flow as a percentage of market capitalization.

1.7%2.9%TMOWin

Net Debt / EBITDA

Net debt relative to EBITDA; a negative value indicates net cash.

0.1x2.6xMSFTWin

Dividend Yield / Payout Ratio

Dividend returns relative to share price and the share of earnings paid as dividends.

0.69% / 19.5%0.27% / 9.6%MSFTWin
TMO offers a higher free cash flow yield, indicating a less demanding valuation. MSFT has the stronger balance sheet, while MSFT provides the higher dividend yield. Overall, the two stocks differ mainly in valuation, financial strength and dividend income.
MSFT vs TMO Returns & Risk

Total Return (Dividend-Adjusted)

Cumulative return over 1, 5 and 10 years, including dividends.

1Y: +0.0%5Y: +81.6%10Y: +787.0%1Y: +46.3%5Y: +17.3%10Y: +326.1%MSFTWin

30-Day Realized Volatility

Annualized volatility based on the past 30 days of daily returns.

22.8%24.3%MSFTWin

Beta (5Y vs S&P 500)

Sensitivity to market movements; above 1 indicates greater market volatility.

1.120.85TMOWin
MSFT has delivered stronger long-term returns, but the risk indicators show mixed results.

MSFT vs TMO Valuation & Dividend Metrics

Review MSFT compared with TMO across valuation, cash flow and dividend metrics, including P/E, forward P/E, free cash flow yield and dividend yield. These figures are provided for reference only and do not represent a fair-value estimate, price target or investment recommendation.

MetricMicrosoft Corp.
MSFT
Thermo Fisher Scientific, Inc.
TMO
Comparison results

Market Cap

$3.82T$249.95BMSFTWin

P/E (TTM)

28.7x35.8xMSFTWin

P/S

11.6x5.4xTMOWin

EV/EBITDA

19.4x25.4xMSFTWin

Dividend Yield

0.69%0.27%MSFTWin

MSFT vs TMO Profitability Over Time

Compare MSFT and TMO across gross margin and operating margin trends over time to understand how each company's profitability has changed. Based on reported financial data only; not a forecast or investment advice.

TTM3Y Avg5Y Avg10Y Avg
MSFT68.4%68.9%68.8%67.3%
TMO40.9%40.7%42.9%44.4%

Technical & Fundamental Stock Analysis

RSI (14, daily)Updated as of 2026-09-28 market close

MSFT 62.49 • TMO 72.89

Measures short-term price momentum and helps identify possible overbought or oversold conditions.

50/200-DMA PositionUpdated as of 2026-09-28 market close

MSFT 50D Above / 200D Above • TMO 50D Above / 200D Above

Shows whether the stock is trading above or below its medium- and long-term trend lines.

R&D % of Revenue

MSFT 10.7% • TMO 3.0%

Shows how much of revenue is invested in research and development.

Share Count Trend (3Y)

MSFT Stable • TMO Decreased

Shows whether the company's share count has increased or decreased over the past three years.

Company Profiles

Microsoft Corp.

Systems Software

Microsoft develops and licenses consumer and enterprise software. It is known for its Windows operating systems and Office productivity suite. The company is organized into three equally sized broad segments: productivity and business processes (legacy Microsoft Office, cloud-based Office 365, Exchange, SharePoint, Skype, LinkedIn, Dynamics), intelligence cloud (infrastructure- and platform-as-a-service offerings Azure, Windows Server OS, SQL Server), and more personal computing (Windows Client, Xbox, Bing search, display advertising, and Surface laptops, tablets, and desktops).

Thermo Fisher Scientific, Inc.

Life Sciences Tools & Services

Thermo Fisher Scientific sells scientific instruments and laboratory equipment, diagnostics consumables, and life science reagents. The firm operates through four segments as of year-end 2025 (revenue figures include some cross-segment revenue): analytical technologies (17% of sales); specialty diagnostic products (11%); life science solutions (23%); and lab products and services, which includes CRO services (the remainder).

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Everything You Need to Know About MSFT vs TMO Stocks

What is MEXC Stock Compare?

MEXC Stock Compare is a side-by-side US stock comparison tool. It helps users compare two companies across stock price performance, market cap, valuation, growth, profitability, balance-sheet strength, dividends and risk. The results are provided for research purposes only and do not constitute investment advice.

Which metrics should I use to evaluate a company's growth?

Start with revenue growth to see how quickly the business is expanding, then review EPS growth to determine whether that growth is translating into higher earnings per share. Gross margin, operating margin and ROIC help assess the quality of that growth by showing profitability and capital efficiency. A company with fast revenue growth but declining margins may be expanding without improving its earnings quality.

How do MSFT and TMO compare in growth and profitability?

In the latest reported period, MSFT recorded revenue growth of +17.8% and TTM EPS growth of +31.7%, compared with +7.2% and +7.4% for TMO. MSFT leads on both growth and profitability. This comparison is based on reported financial metrics and does not predict future performance.

What is the difference between P/E (TTM) and Forward P/E?

P/E (TTM) compares the current share price with actual earnings reported over the past 12 months. Forward P/E uses estimated earnings for the next 12 months, so it reflects market expectations but depends on forecasts that may change. Both ratios should be considered alongside growth, profitability and industry peers.

How do the risk profiles of MSFT and TMO compare?

MSFT has a 30-day realized volatility of 22.8% and a five-year Beta of 1.12, compared with 24.3% and 0.85 for TMO. The risk indicators show mixed results. These indicators describe historical price movements and market sensitivity, but they do not cover every source of investment risk.

What do dividend yield and payout ratio indicate?

Dividend yield shows the annual dividend relative to the current share price, while the payout ratio shows how much of a company's earnings is distributed as dividends. A higher yield may provide more income, but it can also rise because the share price has fallen. Dividend sustainability should therefore be considered together with earnings, cash flow and the payout ratio.

How should I compare a high-growth stock with a lower-valued stock?

A high-growth stock may trade at a higher valuation if investors expect its revenue and earnings to continue expanding. A lower-valued stock may offer a more conservative entry point, but the lower valuation could also reflect slower growth or higher business risk. Growth, valuation, profitability, cash flow and risk should therefore be considered together.

Which is the better stock, MSFT or TMO?

There is no single answer for every investor. Growth-focused investors may place greater weight on revenue growth, EPS growth and ROIC, while income-focused investors may prioritize dividend yield and payout sustainability. Investors with lower risk tolerance may focus more on volatility, Beta and balance-sheet strength. MEXC Stock Compare presents the relevant metrics but does not provide a buy or sell recommendation.

Can I trade MSFT and TMO as RealStocks on MEXC?

Eligible users can trade MSFT and TMO as real US stocks through MEXC RealStocks if both stocks are currently supported. Users must first open and verify a RealStocks account with MEXC's partner licensed broker. RealStocks represents ownership of actual shares rather than tokenized stock exposure. Availability may vary by stock and region, so users should check the corresponding RealStocks trading page before placing an order.

Disclaimer

The stock prices, financial metrics, comparison results and related information displayed on this page are sourced from third-party providers and are provided for informational and educational purposes only. Data may be delayed, incomplete or inaccurate, and MEXC does not guarantee its accuracy, completeness or timeliness. The comparisons and automated summaries do not constitute financial, investment, legal or tax advice, nor a recommendation to buy, sell or hold any security or financial product. Past performance is not indicative of future results. Users should independently verify the information and assess their own objectives, financial circumstances and risk tolerance before making any decision. Where MEXC stock futures or other derivative products are referenced, such products do not represent ownership of the underlying shares and may involve leverage and a substantial risk of loss. Product availability is subject to applicable laws and regional restrictions.