Volition Sponsors Symposium at 15th Conference of the European Hidradenitis Suppurativa Foundation

 Showing New Indication for Nu.Q^® NETs 

HENDERSON, Nev., Feb. 4, 2026 /PRNewswire/ — VolitionRx Limited (NYSE AMERICAN: VNRX) (“Volition”), a multi-national epigenetics company, announces the sponsorship of a symposium at the European Hidradenitis Suppurativa Foundation (EHSF) Conference in Malta on 5^th February. 

The session entitled “Empowering Precision‑medicine approach through NETs Plasma Biomarker‑driven personalized treatment”  will be presented by Professor Evangelos J. Giamarellos-Bourboulis, M.D., PhD, at the 4th Department of Internal Medicine, ATTIKON University General Hospital, Athens, Greece.

Professor Evangelos J. Giamarellos-Bourboulis commented:

“The scientific program at the EHSF conference this year provides a focus on genetics and updates on basic research, including the diagnosis and management of Hidradenitis Suppurativa (HS).

“I am delighted to present data from the recently released clinical study demonstrating the use of Volition’s  Nu.Q^® NETs assay in patient management for HS, a chronic lifelong disease, which affects approximately 1% of the world’s population¹.

“Since the advent of biologicals in the treatment of HS, there has been growing evidence that treatment response varies greatly so that some patients may experience substantial improvement, others no benefit at all and some may even worsen.

“Those considerations call for a precision medicine approach, which will be the focus of the Symposium. The findings from our study demonstrate that for the first time an easy-to-measure blood test, Nu.Q^® NETs, can be used to classify HS patients and help guide treatment selection and modification.

“In addition, given the various biologic therapies currently in development, we will also explore the potential use of circulating H3.1 nucleosomes as a biomarker for ongoing and future clinical studies.

“Our hope is that trials can be started to study if Nu.Q^® NETs can be used to guide both treatment initiation and early cessation of treatment.”

Mr. Remi Rabeuf, VP Corporate Alliances and Strategic Partnership, Volition added:

“We are honored that leading expert Professor Giamarellos-Bourboulis is presenting the findings of his clinical study at the Volition sponsored symposium event at the EHSF Conference this week.

“This study, together with previously published evidence^2-5 , demonstrates that Nu.Q^® NETs should enable clinicians and researchers to anticipate disease, guide treatment decisions, and monitor patients over time, across both acute and chronic conditions.

“The Nu.Q^® NETs assay is CE-Marked to detect diseases associated with NETosis and is therefore approved and commercially available for clinical use in 27 European Union (EU) member states, the three European Economic Area (EEA) countries (Iceland, Liechtenstein, and Norway) and the U.K.

“Nu.Q^® NETs is a simple, low-cost, accessible test to detect diseases associated with NETosis. The market opportunity for such indications is significant, with a Total Addressable Market of $3.8 billion⁶.”

A poster entitled “Change of Neutrophil Extracellular Traps (NETs) Blood Levels to Surrogate Response to Treatment in Hidradenitis Suppurativa” will also be presented at the Conference on Wednesday, February 4.

The recently released paper can be found in link below:

Plasma H3.1-Nucleosomes to Classify Severity and Surrogate Response to Treatment in Hidradenitis Suppurativa : A Cohort Study
 

1. Bouazzi D, Nielsen SM, Hagan PG, et al. JAMA Dermatol. 2025. https://doi.org/10.1001/jamadermatol.2025.2373 
2. Morimont et al. Biomolecules, 2022.  https://doi.org/10.3390/biom12081038
3. Rahimi et al, Ann Intensive Care 2023. https://doi.org/10.1186/s13613-023-01204-y
4. Daan F.L. Filippini et al.. Critical Care, 2025. https://doi.org/10.1186/s13054-025-05415-6
5. Neumann et al, MedRXIV
6. Data on File: Volition TAM Model.

About Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a lifelong, recurring condition that is often difficult to manage. The exact cause of HS is unknown however it is beyond any doubt a chronic neutrophilic disease.

HS is a painful skin condition that causes skin abscesses and scarring on the skin. It is thought to affect about 1 in 100 people.

It is important to recognise and diagnose the condition, including flare-ups, to prevent it getting worse. although the symptoms may improve or eventually stop with treatment.

The condition can have a significant impact on a person’s everyday life. Having to regularly change dressings and constantly live with the pain and discomfort of the symptoms can affect a patient’s  quality of life and lead to depression.

About Volition

Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help detect and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early detection and monitoring have the potential not only to prolong the life of patients, but also to improve their quality of life.

Volition’s research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and an office in London.

The contents found at Volition’s website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.

Media Enquiries: Louise Batchelor, Volition, [email protected], +44 (0)7557 774620

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Nucleosomics, Capture-PCR, Capture-Seq and Nu.Q^® and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release or associated video or link are the property of their respective owners. Additionally, unless otherwise specified, all references to “$” refer to the legal currency of the United States of America.

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SOURCE VolitionRx Limited