Dow Jones
52,395.58
Change
+34.0+0.06%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are mixed today. The Dow Jones is +0.06%, the S&P 500 is +0.57%, and the Nasdaq Composite is +1.12%. Across individual stocks, 2,442 are advancing while 2,675 are declining, suggesting a mixed market tone.
S&P 500
7,720.17
Change
+43.4+0.57%
Nasdaq Composite
26,462.302
Change
+292.921+1.12%
24H Gainers
2,442
24H Losers
2,675
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 51 | MBX Biosciences, Inc.MBX | $52.85 | +5.07% | 115.22K | $2.55B | $16.91 - $72.64 | 0.00% |
| 52 | RF Acquisition Corp IIRFAI | $32.35 | -10.69% | 6.08K | $113.63M | $8.94 - $73.00 | 0.00% |
| 53 | Pulse Biosciences, Inc.PLSE | $52.90 | +0.38% | 141.48K | $3.75B | $12.56 - $58.90 | 0.00% |
| 54 | Western Digital Corp.WDC | $382.25 | +7.15% | 5.73M | $143.08B | $121.85 - $799.87 | 0.00% |
| 55 | Seagate Technology Holdings PLCSTX | $675.68 | +4.85% | 4.42M | $153.65B | $217.67 - $1,145.00 | 0.00% |
| 56 | Tango Therapeutics, Inc.TNGX | $22.66 | +2.30% | 1.45M | $3.82B | $7.12 - $34.39 | 0.00% |
| 57 | Forum Energy Technologies, Inc.FET | $90.13 | +1.27% | 46.50K | $1.01B | $26.00 - $91.53 | 0.00% |
| 58 | Bandwidth Inc.BAND | $49.24 | +4.88% | 267.59K | $1.49B | $12.50 - $79.08 | 0.00% |
| 59 | RINGCENTRAL, INC.RNG | $86.49 | -0.21% | 705.23K | $6.46B | $24.14 - $98.14 | 0.00% |
| 60 | Fossil Group, Inc.FOSL | $6.54 | +2.03% | 205.09K | $387.06M | $1.70 - $7.39 | 0.00% |
| 61 | Lindblad Expeditions Holdings Inc.LIND | $35.73 | +3.54% | 265.21K | $2.34B | $11.37 - $36.97 | 0.00% |
| 62 | Okeanis Eco Tankers Corp.ECO | $94.31 | -2.48% | 476.31K | $3.70B | $31.75 - $100.68 | 0.00% |
| 63 | Vera Bradley, Inc.VRA | $6.13 | +3.19% | 216.39K | $176.00M | $1.39 - $6.43 | 0.00% |
| 64 | Vestis CorporationVSTS | $15.00 | +0.40% | 571.88K | $1.98B | $4.83 - $16.90 | 0.00% |
| 65 | Illumina Inc.ILMN | $280.48 | +3.88% | 922.76K | $42.35B | $94.00 - $309.35 | 0.00% |
| 66 | Shattuck Labs, Inc.STTK | $5.75 | +3.25% | 191.29K | $577.09M | $1.72 - $8.33 | 0.00% |
| 67 | Syntec Optics Holdings, Inc.OPTX | $7.04 | +6.10% | 87.78K | $283.53M | $1.18 - $14.92 | 0.00% |
| 68 | Nuvectis Pharma, Inc.NVCT | $18.18 | +0.16% | 71.51K | $593.31M | $5.55 - $29.27 | 0.00% |
| 69 | Marvell Technology, Inc.MRVL | $243.03 | +3.45% | 8.29M | $213.11B | $70.69 - $329.88 | 0.00% |
| 70 | StablecoinX Inc.USDE | $10.10 | -5.16% | 504.13K | $251.11M | $1.33 - $18.11 | 0.00% |
| 71 | AN2 Therapeutics, Inc.ANTX | $3.65 | +0.96% | 121.27K | $137.93M | $1.00 - $7.19 | 0.00% |
| 72 | Andersen Group Inc.ANDG | $63.27 | -1.56% | 60.65K | $1.18B | $18.12 - $65.94 | 0.00% |
| 73 | Eton Pharmaceutcials, Inc.ETON | $49.72 | -1.43% | 113.52K | $1.42B | $14.27 - $66.37 | 0.00% |
| 74 | DigitalOcean Holdings, Inc.DOCN | $107.39 | +7.77% | 1.47M | $11.21B | $37.84 - $187.50 | 0.00% |
| 75 | Pyxis Tankers Inc.PXS | $7.33 | -4.50% | 88.77K | $75.04M | $2.56 - $8.34 | 0.00% |
| 76 | Aura Minerals Inc.AUGO | $81.36 | +5.46% | 291.75K | $6.82B | $29.11 - $110.32 | 0.00% |
| 77 | Globus Maritime LimitedGLBS | $3.00 | +0.67% | 46.69K | $64.75M | $1.04 - $4.06 | 0.00% |
| 78 | Penguin Solutions, Inc.PENG | $59.55 | +7.19% | 1.25M | $3.59B | $16.04 - $89.86 | 0.00% |
| 79 | Hyperliquid Strategies Inc.PURR | $10.02 | +10.80% | 6.74M | $1.74B | $3.01 - $14.76 | 0.00% |
| 80 | LifeStance Health Group, Inc.LFST | $13.06 | +0.08% | 981.78K | $4.99B | $4.77 - $13.56 | 0.00% |
| 81 | Iridium Communications Inc.IRDM | $45.81 | +2.98% | 240.05K | $4.86B | $15.64 - $57.18 | 0.01% |
| 82 | NGL ENERGY PARTNERS LPNGL | $16.12 | +1.64% | 15.55K | $2.01B | $6.26 - $19.06 | 0.05% |
| 83 | Ethos Technologies Inc.LIFE | $42.75 | +1.75% | 579.51K | $2.80B | $9.45 - $44.99 | 0.00% |
| 84 | Aehr Test SystemsAEHR | $63.69 | +12.10% | 1.58M | $2.08B | $18.70 - $147.40 | 0.00% |
| 85 | TOP Financial Group LimitedTOP | $15.31 | +0.79% | 116.65K | $1.86B | $3.06 - $17.42 | 0.00% |
| 86 | Relay Therapeutics, Inc.RLAY | $18.68 | +2.65% | 981.33K | $4.09B | $5.95 - $21.27 | 0.00% |
| 87 | FIGS, Inc.FIGS | $20.55 | -1.56% | 1.10M | $3.24B | $7.21 - $20.89 | 0.00% |
| 88 | Okta, Inc.OKTA | $226.53 | +2.89% | 1.30M | $37.86B | $62.66 - $235.00 | 0.00% |
| 89 | Hewlett Packard Enterprise CompanyHPE | $60.84 | +3.70% | 6.40M | $80.77B | $19.84 - $73.56 | 0.01% |
| 90 | Paysign, Inc.PAYS | $14.67 | +3.26% | 342.03K | $828.30M | $3.08 - $16.15 | 0.00% |
| 91 | Guardant Health, Inc.GH | $177.62 | +2.07% | 632.23K | $23.84B | $68.02 - $191.05 | 0.00% |
| 92 | Edgewise Therapeutics, Inc.EWTX | $39.63 | +0.83% | 268.96K | $4.30B | $15.23 - $48.51 | 0.00% |
| 93 | First Tracks Biotherapeutics, Inc.TRAX | $45.96 | +5.24% | 311.75K | $1.57B | $14.72 - $49.91 | 0.00% |
| 94 | Tilly's Inc.TLYS | $4.17 | -0.24% | 58.78K | $97.08M | $1.14 - $6.25 | 0.00% |
| 95 | Calumet, Inc.CLMT | $49.61 | -4.73% | 593.30K | $4.36B | $17.85 - $59.87 | 0.00% |
| 96 | Maravai LifeSciences Holdings, Inc.MRVI | $8.16 | +7.52% | 942.76K | $1.22B | $2.54 - $9.42 | 0.00% |
| 97 | FormFactor Inc.FORM | $106.93 | +5.81% | 594.42K | $8.34B | $41.84 - $160.27 | 0.00% |
| 98 | Hongli Group Inc.HLP | $3.56 | +1.00% | 187.49K | $266.07M | $0.34 - $3.63 | 0.00% |
| 99 | Definium Therapeutics, Inc.DFTX | $37.50 | +4.68% | 624.93K | $5.04B | $14.62 - $49.70 | 0.00% |
| 100 | Glaukos CorporationGKOS | $183.81 | +3.12% | 771.67K | $10.84B | $73.16 - $191.62 | 0.00% |
Trade U.S. stocks Your Way on MEXC
| RealStocks | Tokenized Stocks | Stock Futures | |
|---|---|---|---|
| What it is | RealStocks — real shares of U.S.-listed companies | Blockchain-based tokens linked to U.S. stocks/ETFs | USDT-margined futures on U.S. stock price movements |
| Ownership | Yes — actual shares | No — synthetic exposure only | No — derivative exposure only |
| Shareholder rights | Yes (e.g. dividends) | No | No |
| Trading hours | U.S. market sessions (pre-market, regular, after-hours, overnight) | 24/7 | Up to 24/7 (supported pairs) |
| Position types | Buy and hold | Buy and hold | Long, short, leveraged |
| Best for | Long-term investors seeking ownership and dividend income | Traders wanting round-the-clock access to stock exposure without holding shares | Active/short-term traders looking to speculate or hedge with leverage |
RealStocks
Tokenized Stocks
Stock FuturesWhy Trade U.S. stocks on MEXC?
RealStocks, Real Ownership
Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.
.b39e813829fa.png)
7,000+ U.S. stocks & ETFs
Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.
.b39e815d234d.png)
Seamless USDT-to-Stock Access
Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.
.b39e81c62f33.png)
.b39e81f7d220.png)
Lower-Cost Stock Trading
Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.
Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
MBX Biosciences, Inc. (MBX) currently leads with a 52-week gain of 203.04% as of 2026-10-27 17:38 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
Nvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBV
Nvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBVNvidia Corp.NVDAAlphabet Inc.GOOGBroadcom Inc.AVGOEli Lilly & Co.LLYVISA Inc.VABBVIE INC.ABBV
Apple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTRApple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTRApple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTRApple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTR
Apple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTRApple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTRApple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTRApple Inc.AAPLAmazon.Com Inc.AMZNTesla, Inc.TSLAMicron Technology, Inc.MUExxon Mobil CorporationXOMPalantir Technologies Inc.PLTR
Alphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTCAlphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTCAlphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTCAlphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTC
Alphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTCAlphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTCAlphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTCAlphabet Inc.GOOGLSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AWalmart Inc.WMTJohnson & JohnsonJNJIntel Corp.INTC
Microsoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVXMicrosoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVXMicrosoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVXMicrosoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVX
Microsoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVXMicrosoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVXMicrosoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVXMicrosoft Corp.MSFTMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BAdvanced Micro DevicesAMDMastercard IncorporatedMAChevron CorporationCVX
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.