52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are broadly higher today, with the Dow Jones up ⁦0.16%⁩, the S&P 500 up ⁦0.76%⁩, and the Nasdaq Composite up ⁦1.40%⁩. Market breadth is also positive, with 2,594 stocks advancing versus 2,524 declining, indicating a broadly bullish bias.

Dow Jones

52,447.13

Change

+85.55+0.16%

S&P 500

7,734.88

Change

+58.11+0.76%

Nasdaq Composite

26,536.64

Change

+367.259+1.40%

24H Gainers

2,594

24H Losers

2,524

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
251	Alto Neuroscience Inc.ANRO	$23.18	+4.77%	267.03K	$909.83M	$10.20 - $37.48	0.00%
252	NetSol Technologies, Inc.NTWK	$8.32	+8.83%	210.05K	$99.51M	$2.73 - $8.38	0.00%
253	Starz Entertainment Corp.STRZ	$21.39	+2.53%	169.20K	$379.99M	$8.40 - $32.58	0.00%
254	NRC HealthNRC	$21.55	-3.47%	52.91K	$485.55M	$11.32 - $23.68	0.03%
255	Lionsgate Studios Corp.LION	$12.26	+0.86%	1.50M	$3.72B	$6.14 - $16.70	0.00%
256	Greif, Inc.GEF.B	$116.17	+1.04%	127.26K	$2.48B	$57.63 - $116.78	0.03%
257	Palvella Therapeutics, Inc.PVLA	$132.53	+4.27%	94.40K	$1.80B	$68.96 - $161.38	0.00%
258	Enerflex Ltd.EFXT	$23.90	+2.39%	167.46K	$2.92B	$12.46 - $29.15	0.00%
259	Delek US Holdings, Inc.DK	$70.98	-9.39%	998.54K	$4.35B	$25.85 - $82.27	0.01%
260	Vir Biotechnology, Inc.VIR	$11.59	+4.26%	1.22M	$1.96B	$4.82 - $12.00	0.00%
261	Talos Energy, Inc.TALO	$18.22	-1.70%	1.55M	$3.04B	$9.35 - $18.73	0.00%
262	VersaBankVBNK	$22.41	-3.77%	87.42K	$728.02M	$11.25 - $25.05	0.00%
263	Nucor CorporationNUE	$269.14	+4.74%	1.66M	$61.06B	$139.21 - $280.11	0.01%
264	Liquidity Services, Inc.LQDT	$44.92	-0.53%	85.15K	$1.41B	$21.67 - $45.80	0.00%
265	Patterson-UTI Energy Inc.PTEN	$12.22	+0.20%	2.80M	$4.66B	$5.24 - $13.39	0.03%
266	Protagonist Therapeutics, Inc.PTGX	$140.15	-0.12%	282.25K	$9.07B	$74.03 - $160.81	0.00%
267	Myers Industries, Inc.MYE	$32.37	+0.98%	114.00K	$1.22B	$16.46 - $37.45	0.02%
268	The Chef's Warehouse Inc.CHEF	$108.43	+1.05%	313.21K	$4.42B	$56.46 - $118.51	0.00%
269	Slide Insurance Holdings, Inc.SLDE	$28.60	-1.75%	1.10M	$3.33B	$15.11 - $30.30	0.00%
270	Eagle Bancorp Inc.EGBN	$32.96	-1.05%	238.65K	$1.00B	$15.03 - $34.09	0.01%
271	SM Energy CompanySM	$39.14	-2.44%	1.31M	$9.31B	$17.45 - $41.56	0.02%
272	Cenovus Energy Inc.CVE	$31.75	-3.65%	4.25M	$57.67B	$15.63 - $34.16	0.00%
273	Flexsteel IndustriesFLXS	$66.74	-18.22%	146.19K	$357.41M	$34.00 - $90.64	0.01%
274	Bank of the James Financial Group, Inc.BOTJ	$30.10	+0.95%	21.72K	$136.75M	$15.72 - $30.86	0.01%
275	United Fire Group Inc.UFCS	$57.31	-0.21%	42.87K	$1.47B	$29.85 - $58.20	0.01%
276	Cullinan Therapeutics, Inc.CGEM	$14.89	+2.17%	242.16K	$958.05M	$6.73 - $23.19	0.00%
277	NN Inc.NNBR	$3.54	+5.51%	2.01M	$332.32M	$1.10 - $4.79	0.00%
278	Commercial Vehicle Group, Inc.CVGI	$3.04	+7.89%	140.37K	$123.73M	$1.29 - $5.88	0.00%
279	Par Pacific Holdings, Inc.PARR	$75.28	-9.46%	605.29K	$3.77B	$34.37 - $90.74	0.00%
280	Arrow Electronics, Inc.ARW	$219.82	+1.91%	285.62K	$11.19B	$101.79 - $249.43	0.00%
281	Amalgamated Financial Corp.AMAL	$51.69	+1.20%	158.21K	$1.55B	$26.61 - $51.88	0.01%
282	Richardson Electronics LtdRELL	$19.86	+6.69%	136.33K	$255.04M	$9.37 - $23.15	0.01%
283	Permian Basin Royalty TrustPBT	$33.17	-1.16%	41.12K	$1.55B	$16.25 - $37.00	0.00%
284	Palo Alto Networks, Inc.PANW	$402.73	+2.85%	3.30M	$329.43B	$139.57 - $432.32	0.00%
285	VERMILION ENERGY INC.VET	$13.63	-3.30%	1.24M	$2.07B	$7.21 - $14.82	0.00%
286	Charles River Laboratories International, Inc.CRL	$356.64	-0.13%	656.55K	$17.03B	$146.19 - $360.40	0.00%
287	Texas Instruments IncorporatedTXN	$308.39	+3.09%	3.45M	$281.63B	$152.73 - $334.03	0.02%
288	SOPHiA GENETICS SASOPH	$7.64	+1.46%	209.57K	$640.96M	$3.83 - $8.98	0.00%
289	Riskified Ltd.RSKD	$8.94	-2.52%	780.39K	$929.54M	$3.70 - $9.29	0.00%
290	BJ's Restaurants, Inc.BJRI	$57.19	-0.67%	254.73K	$1.22B	$28.46 - $74.60	0.00%
291	NWPX Infrastructure, Inc.NWPX	$99.52	+2.77%	104.21K	$959.09M	$53.15 - $152.03	0.00%
292	Qualys, Inc.QLYS	$228.62	+1.36%	447.25K	$7.91B	$74.51 - $230.90	0.00%
293	Avnet, Inc.AVT	$92.62	+2.61%	317.00K	$7.62B	$44.25 - $108.63	0.02%
294	ATI Inc.ATI	$165.97	+1.24%	1.60M	$22.60B	$90.00 - $243.57	0.00%
295	SFL Corporation Ltd.SFL	$12.71	-0.20%	554.87K	$1.84B	$6.99 - $13.98	0.00%
296	InnovAge Holding Corp.INNV	$9.07	-2.05%	234.06K	$1.24B	$3.94 - $12.64	0.00%
297	Skeena Resources LimitedSKE	$29.13	+5.20%	302.95K	$3.66B	$15.43 - $38.77	0.00%
298	Diamondrock Hospitality CompanyDRH	$14.12	+0.97%	1.38M	$2.89B	$7.58 - $14.15	0.03%
299	Integer Holdings CorporationITGR	$126.61	+0.10%	383.87K	$4.30B	$62.00 - $126.92	0.00%
300	Viatris Inc.VTRS	$18.77	+2.46%	3.82M	$21.56B	$9.92 - $18.82	0.00%

1
•••
4
5
6
7
8
•••
104

Deposit USD for Up to $520

First USD deposit earns $20 with 0 fees

Trade U.S. stocks Your Way on MEXC

	RealStocks	Tokenized Stocks	Stock Futures
What it is	RealStocks — real shares of U.S.-listed companies	Blockchain-based tokens linked to U.S. stocks/ETFs	USDT-margined futures on U.S. stock price movements
Ownership	Yes — actual shares	No — synthetic exposure only	No — derivative exposure only
Shareholder rights	Yes (e.g. dividends)	No	No
Trading hours	U.S. market sessions (pre-market, regular, after-hours, overnight)	24/7	Up to 24/7 (supported pairs)
Position types	Buy and hold	Buy and hold	Long, short, leveraged
Best for	Long-term investors seeking ownership and dividend income	Traders wanting round-the-clock access to stock exposure without holding shares	Active/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Alto Neuroscience Inc. (ANRO) currently leads with a 52-week gain of 89.27% as of 2026-10-27 19:37 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.