American Heart Association Funds $3.4 Million in Cardiac Arrest Research Through New CART Network

The American Heart Association is investing $3.4 million in two research teams to lead new studies aimed at improving cardiac arrest outcomes, as part of a newly established Cardiac Arrest Research Team (CART) Network in collaboration with Heart & Stroke of Canada. With more than 600,000 cardiac arrests occurring annually in the U.S. and survival rates remaining low, this initiative seeks to accelerate scientific discoveries and translate them into practice.

One team, led by Joshua Lupton, M.D., M.P.H., M.Phil., from Oregon Health & Science University (OHSU) and himself a cardiac arrest survivor, will focus on out-of-hospital cardiac arrest. The study will examine the placement of defibrillator pads to optimize shock delivery, using AI to analyze timing between shocks. Researchers will also work with survivors to identify best practices for post-arrest support and peer connections. The goal is to improve care from emergency treatment through recovery.

The second team, led by Ari Moskowitz, M.D., M.P.H., FAHA, from Albert Einstein College of Medicine and Montefiore Health System, will investigate vasopressor strategies to improve brain and organ function after cardiac arrest. The VICTORY-CART study will compare two commonly used blood pressure medications to determine which leads to better survival and recovery. The team aims to establish a learning health system framework to standardize effective treatments across hospitals.

Both teams will collaborate with Canadian scientists and incorporate insights from survivors, family members, and those who have lost loved ones. ‘Cardiac arrest is a profound and tragic occurrence and we know seconds matter,’ said Stacey E. Rosen, M.D., FAHA, volunteer president of the American Heart Association. The research aligns with the Association’s Emergency Cardiovascular Care 2030 Impact Goals to double cardiac arrest survival rates within five years.

The four-year grants begin July 1, 2026. The American Heart Association has funded over $6.1 billion in cardiovascular research since 1949, making it the largest non-profit supporter of heart and brain health research in the U.S. According to a recent Annenberg Policy Center poll, 82% of U.S. adults trust the Association for public health information.

For more information, visit heart.org or newmediawire.com.

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